Peer-reviewed Journal: The Primo Vascular System: A Unique Human Biological System Shifting Medical Paradigm - Prospective Osteopathic Applications for Cranial, Visceral, Lymphatic, and Fascial Techniques, Chikly B, Roberts P, Quaghebeur J, Journal of American Osteopathic Assocation (JAOA), 2016, Jan

The primo-vascular vessels (PVS) constitute a novel human biological system, a changing paradigm in medicine.

Envision its prospective applications for manual therapy. In the early 1960's, a remarkable scientific discovery was made in North Korea, though went virtually unnoticed and unrecognized for nearly 40 years until 2002, where it resurfaced slowly emerging as a novel anatomical structure.

This very unique anatomo-physiologic system, entitled “primo-vascular system” (PVS), is depicted as a novel circulatory system, though set apart from those of the arterio-venous, lymphatic, and cerebrospinal systems.

It comprises immune functions, some endocrine functions and is found deeply involved in pathological processes including inflammation and cancer.

The verification of PVS presence in intravascular and extravascular spaces, on the surface of viscera, within the CNS, in cutaneous layers, and most body systems may signify a novel and complete morpho-dynamic system with potential to shift paradigms in medicine and manual therapy.

Concordance of PVS research and clinical practice may expand horizons in osteopathic manual medicine and manual therapy.


Class Code
Brain Curriculum
Lymph Drainage Therapy